Zef A. Könst

Site-Selective Aliphatic C–H Chlorination Using <i>N</i>-Chloroamides Enables a Synthesis of Chlorolissoclimide

Ryan K. Quinn, Zef A. Könst, Sharon E. Michalak et al. · Journal of the American Chemical Society · 2015 · 280 citations · Full text

Natural Sciences, Chemistry, Green Chemistry +9

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies

Daniel Robbins, Mark Noviski, Ying Siow Tan et al. · Journal of Medicinal Chemistry · 2024 · 96 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

Zef A. Könst, Anne R. Szklarski, Simone Pellegrino et al. · Nature Chemistry · 2017 · 46 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1

Andrew M. White, Kathy Dao, Darius Vrubliauskas et al. · The Journal of Organic Chemistry · 2017 · 27 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

Simone Pellegrino, Mélanie Meyer, Zef A. Könst et al. · Nucleic Acids Research · 2019 · 20 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +13