Semaglutide lowers body weight in rodents via distributed neural pathways

Sanaz Gabery, Casper G. Salinas, Sarah Juel Paulsen, +22

JCI Insight

Food IntakePharmacotherapyExperimental PharmacologyNeuromuscular BlockadeGastrointestinal Peptide Hormone +21

Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist

Stephen T. Buckley, Tine A. Bækdal, Andreas Vegge, +19

Science Translational Medicine

Tomographic molecular imaging and 3D quantification within adult mouse organs

Tomas Alanentalo, Amir Asayesh, Harris Morrison, +4

Nature Methods

Tomographic Molecular ImagingTissue ImagingEngineeringMedical ImagingNovel Imaging Method +10

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

Violeta Georgieva Tsonkova, Fredrik Wolfhagen Sand, Xenia Asbæk Wolf, +33

Molecular Metabolism

Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of β-Cells in Murine Type 1 Diabetes

Tomas Alanentalo, Andreas Hörnblad, Sofia Mayans, +5

Diabetes

Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment

Casper Bo Gravesen Salinas, Tess Tsai-Hsiu Lu, Sanaz Gabery, +9

Scientific Reports

High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas

Tomas Alanentalo, Christina E. Lorén, Åsa Larefalk, +3

Journal of Biomedical Optics

EngineeringMicroscopyImmunologyPathologyHigh-resolution Three-dimensional Imaging +20

Illuminating the complete ß-cell mass of the human pancreas- signifying a new view on the islets of Langerhans

Joakim Lehrstrand, Wayne I. L. Davies, Max Hahn, +3

Nature Communications

Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes

Max Hahn, Pim P. van Krieken, Christoffer Nord, +12

Communications Biology

Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research

Anna Eriksson, Christoffer Svensson, Andreas Hörnblad, +9

Journal of Visualized Experiments