Sylvie Chamoin

The Suzuki-Miyaura cross coupling reactions on solid support. Link to solution phase directed ortho metalation. The Leznoff acetal linker approach to biaryl and heterobiaryl aldehydes

Sylvie Chamoin, Stephen Houldsworth, Chris G. Kruse et al. · Tetrahedron Letters · 1998 · 53 citations

Materials Science, Cross-coupling Reaction, Ortho Metalation +6

The Stille cross coupling reactions on solid support. Link to solution phase directed ortho metalation. An ester linker approach to styryl, biaryl and heterobiaryl car☐ylic acids

Sylvie Chamoin, Stephen Houldsworth, Victor Snieckus · Tetrahedron Letters · 1998 · 49 citations

Chemical Engineering, Ortho Metalation, Engineering +6

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

Duncan Shaw, Ferheen Baig, Ian Bruce et al. · Journal of Medicinal Chemistry · 2016 · 23 citations · Full text

Pdgfr Kinase Domain, Pulmonary Arterial Hypertension, Pulmonary Circulation +13

Facile and Mild Synthesis of Linear and Cyclic Peptides via Thioesters

Paola Agrigento, Fernando Alberício, Sylvie Chamoin et al. · Organic Letters · 2014 · 17 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +15

Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization

Alexei S. Karpov, Cristina Nieto‐Oberhuber, Tinya J. Abrams et al. · ACS Medicinal Chemistry Letters · 2019 · 15 citations · Full text