Michelle J. Porritt

Can Animal Models of Disease Reliably Inform Human Studies?

H. Bart van der Worp, David W. Howells, Emily S. Sena et al. · PLoS Medicine · 2010 · 1.3K citations · Full text

Activated Macrophages and Microglia Induce Dopaminergic Sprouting in the Injured Striatum and Express Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor

Peter Batchelor, Gabriel T. Liberatore, J Wong et al. · Journal of Neuroscience · 1999 · 572 citations · Full text

Inflammation, Macrophages Expresses, Nigrostriatal Dopaminergic Neurons +14

Reduced BDNF mRNA Expression in the Parkinson's Disease Substantia Nigra

David W. Howells, Michelle J. Porritt, J Wong et al. · Experimental Neurology · 2000 · 500 citations

Medicine, Parkinson Disease, Bdnf Mrna Expression +7

Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq

Beeke Wienert, Stacia K. Wyman, Chris D. Richardson et al. · Science · 2019 · 408 citations

In vivo CRISPR editing with no detectable genome-wide off-target mutations

Pınar Akçakaya, Maggie Bobbin, Jimmy A. Guo et al. · Nature · 2018 · 315 citations · Full text

Vivo Crispr, Natural Sciences, Genetics +8