Katherine Ewings

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib et al. · Nature Communications · 2021 · 336 citations · Full text

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

Rebecca Ley, Katherine Ewings, Kathryn Hadfield et al. · Cell Death and Differentiation · 2005 · 305 citations

Regulatory Phosphorylation, Signal Transduction, Signaling Pathway +10

Extracellular Signal-regulated Kinases 1/2 Are Serum-stimulated “BimEL Kinases” That Bind to the BH3-only Protein BimEL Causing Its Phosphorylation and Turnover

Rebecca Ley, Katherine Ewings, Kathryn Hadfield et al. · Journal of Biological Chemistry · 2004 · 187 citations · Full text

Peptidylprolyl Isomerase, Apoptosis, Cell Death +18

ERK1/2‐dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl‐1 and Bcl‐xL

Katherine Ewings, Kathryn Hadfield-Moorhouse, Ceri M. Wiggins et al. · The EMBO Journal · 2007 · 172 citations · Full text

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

Grace E. Snow, Allison C Kasper, Alexander M. Busch et al. · BMC Cancer · 2009 · 33 citations · Full text