Concepedia
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Publications
18
Citations
1.5K
H-Index
15
Active since
1985
Affiliations
Fox Chase Cancer Center(Current)
Cancer Research Center
National Cancer Institute
George Merkel is an author at Fox Chase Cancer Center specializing in virology, medicine, and molecular biology.
Top concepts
MedicineVirologyMolecular BiologyNatural SciencesImmunologyBiochemistryDna ReplicationSystems BiologyPathogenesisProtein Folding
Publications per year
1985–2013
The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro
Richard A. Katz, George Merkel, Joseph Kulkosky et al. · Cell · 1990 · 348 citations
Viral Replication, Developmental Biology, Molecular Virology +7
High-resolution Structure of the Catalytic Domain of Avian Sarcoma Virus Integrase
Grzegorz Bujacz, Mariusz Jaskólski, Jerry Alexandratos et al. · Journal of Molecular Biology · 1995 · 226 citations
Virus Structure, Catalytic Domain, Molecular Biology +6
Retroviral integrase functions as a multimer and can turn over catalytically.
Kathryn S. Jones, John W. Coleman, George Merkel et al. · Journal of Biological Chemistry · 1992 · 146 citations · Full text
Retroviral Integrase Functions, Viral Replication, Systems Biology +15
Binding of Different Divalent Cations to the Active Site of Avian Sarcoma Virus Integrase and Their Effects on Enzymatic Activity
Grzegorz Bujacz, Jerry Alexandratos, Alexander Wlodawer et al. · Journal of Biological Chemistry · 1997 · 144 citations · Full text
Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response
René Daniel, Gary D. Kao, Konstantin D. Taganov et al. · Proceedings of the National Academy of Sciences · 2003 · 100 citations · Full text
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