Lakshmi Kavitha Sthanam

KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells

Krishnan K. Mahadevan, Kathleen M. McAndrews, Valerie S. LeBleu et al. · Cancer Cell · 2023 · 193 citations · Full text

Tumor Biology, Krasg12d Inhibition, Cancer Immunosurveillance +11

Membrane Vesicles of Group B Streptococcus Disrupt Feto-Maternal Barrier Leading to Preterm Birth

Manalee Vishnu Surve, Anjali Anil, Kshama Ganesh Kamath et al. · PLoS Pathogens · 2016 · 142 citations · Full text

Immunology, Gynecology, Inflammation +16

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

Krishnan K. Mahadevan, Valerie S. LeBleu, Elena V. Ramirez et al. · Developmental Cell · 2023 · 59 citations · Full text

Oncogenic Kras, Pancreatic Cancer, Oncogenic Agent +7

Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer

Krishnan K. Mahadevan, Allison M. Dyevoich, Yang Chen et al. · Science · 2024 · 36 citations · Full text

Biophysical regulation of mouse embryonic stem cell fate and genomic integrity by feeder derived matrices

Lakshmi Kavitha Sthanam, Amlan Barai, Anuj Rastogi et al. · Biomaterials · 2016 · 27 citations

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +11