Krishnan K. Mahadevan

Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

Yang Chen, Sujuan Yang, Jena Tavormina et al. · Cancer Cell · 2022 · 306 citations · Full text

Medicine, Cancer Biology, Oncology +17

KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells

Krishnan K. Mahadevan, Kathleen M. McAndrews, Valerie S. LeBleu et al. · Cancer Cell · 2023 · 228 citations · Full text

Medicine, Cancer Biology, Oncology +17

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

Krishnan K. Mahadevan, Valerie S. LeBleu, Elena V. Ramirez et al. · Developmental Cell · 2023 · 65 citations · Full text

Medicine, Cancer Biology, Oncology +17

Oesophageal intrasquamous IgG4 deposits: an adjunctive marker to distinguish eosinophilic oesophagitis from reflux oesophagitis

Lawrence Zukerberg, Krishnan K. Mahadevan, Martin K. Selig et al. · Histopathology · 2015 · 54 citations · Full text

Medicine, Pathology, Gastroenterology +15

Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer

Krishnan K. Mahadevan, Allison M. Dyevoich, Yang Chen et al. · Science · 2024 · 50 citations · Full text

Medicine, Immunology, Oncology +17