Iain A. S. Walters

Asymmetric synthesis of anti-α-alkyl-β-amino acids

Stephen G. Davies, Iain A. S. Walters · Journal of the Chemical Society Perkin Transactions 1 · 1994 · 106 citations

Derivatives, Engineering, Biochemistry +13

Asymmetric synthesis of syn-α-alkyl-β-amino acids

Stephen G. Davies, Osamu Ichihara, Iain A. S. Walters · Journal of the Chemical Society Perkin Transactions 1 · 1994 · 93 citations

Engineering, Biochemistry, Natural Sciences +12

Asymmetric synthesis of (–)-(1R,2S)-cispentacin and related cis- and trans-2-amino cyclopentane- and cyclohexane-1-carboxylic acids

Stephen G. Davies, Osamu Ichihara, Isabelle Lenoir et al. · Journal of the Chemical Society Perkin Transactions 1 · 1994 · 88 citations

Cyclohexane-1-carboxylic Acids, Cyclohexane Homologue 14, Organic Chemistry +17

Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A₂ Based on a 1,3-Disubstituted Propan-2-one Skeleton

Stephen Connolly, Colin Bennion, Sarah Botterell et al. · Journal of Medicinal Chemistry · 2002 · 84 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Enzyme Active Site +15

Identification of the Clinical Candidate (<i>R</i>)-(1-(4-Fluorophenyl)-6-((1-methyl-1<i>H</i>-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1<i>H</i>-pyrazolo[3,4-<i>g</i>]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist

Hazel Hunt, Joseph K. Belanoff, Iain A. S. Walters et al. · Journal of Medicinal Chemistry · 2017 · 64 citations · Full text

Clinical Candidate, Pharmacotherapy, Glucocorticoid +17