Hazel Hunt

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

Leandro F. Vendruscolo, David Estey, Vivian Goodell et al. · Journal of Clinical Investigation · 2015 · 222 citations · Full text

Medicine, Neuroscience, Pharmacology +15

Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator

Ioannis Zalachoras, René Houtman, Erika Atucha et al. · Proceedings of the National Academy of Sciences · 2013 · 117 citations · Full text

Veterinary Medicine, Neuroscience, Pharmacology +17

New selective glucocorticoid receptor modulators reverse amyloid-β peptide–induced hippocampus toxicity

Fanny Pineau, Geoffrey Canet, Catherine Desrumaux et al. · Neurobiology of Aging · 2016 · 67 citations

Medicine, Neuroscience, Pharmacology +16

Identification of the Clinical Candidate (<i>R</i>)-(1-(4-Fluorophenyl)-6-((1-methyl-1<i>H</i>-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1<i>H</i>-pyrazolo[3,4-<i>g</i>]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist

Hazel Hunt, Joseph K. Belanoff, Iain A. S. Walters et al. · Journal of Medicinal Chemistry · 2017 · 67 citations · Full text

Medicine, Endocrinology, Pharmacology +8

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double‐Blind, Randomized, Placebo‐Controlled Phase 1 Clinical Study

Hazel Hunt, Kirsteen Donaldson, Mark Strem et al. · Clinical Pharmacology in Drug Development · 2017 · 63 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +9