Fidel Huerta

Cereblon covalent modulation through structure-based design of histidine targeting chemical probes

Justin T. Cruite, Geoffrey P. Dann, Jianwei Che et al. · RSC Chemical Biology · 2022 · 60 citations · Full text

Drug Target, Molecular Biology, Electrophilic Biocompatible Warheads +20

Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions

Yang Gao, Baishan Jiang, Hellen Kim et al. · Journal of Medicinal Chemistry · 2023 · 37 citations · Full text

Molecular Biology, Catalytic Degraders, Multiple Catalytic Degraders +17

Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead

Radosław P. Nowak, Leah Ragosta, Fidel Huerta et al. · RSC Chemical Biology · 2023 · 35 citations · Full text

Tuning site-specific dynamics to drive allosteric activation in a pneumococcal zinc uptake regulator

Daiana A. Capdevila, Fidel Huerta, Katherine A. Edmonds et al. · eLife · 2018 · 29 citations · Full text

HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development

Tiffany Tsang, Fidel Huerta, Yingpeng Liu et al. · ACS Chemical Biology · 2023 · 16 citations

Biomolecular Tool, Minimal Tag, Molecular Biology +21