Guodong Mao

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 171 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3<i>H</i>]indol]-2′(1′<i>H</i>)-ones as Orally Bioavailable Antitumor Agents

Peter B. Sampson, Yong Liu, Narendra Kumar Patel et al. · Journal of Medicinal Chemistry · 2014 · 111 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

The Discovery of PLK4 Inhibitors: (<i>E</i>)-3-((1<i>H</i>-Indazol-6-yl)methylene)indolin-2-ones as Novel Antiproliferative Agents

Radoslaw S. Laufer, Bryan Forrest, Sze-Wan Li et al. · Journal of Medicinal Chemistry · 2013 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1<i>H</i>-indazole-5-carboxamides as Anticancer Agents

Yong Liu, Yunhui Lang, Narendra Kumar Patel et al. · Journal of Medicinal Chemistry · 2015 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides

Radoslaw S. Laufer, Grace Ng, Yong Liu et al. · Bioorganic & Medicinal Chemistry · 2014 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9