Isolation and characterization of the nephritogenic antigen producing anti-tubular basement membrane disease.

Michael D. Clayman, A Martínez-Hernández, L Michaud, +4

The Journal of Experimental Medicine

Laboratory ImmunologyRenal PathologyImmunologyExperimental PathologyPathology +21

Isolation of the target antigen of human anti-tubular basement membrane antibody-associated interstitial nephritis.

Michael D. Clayman, L Michaud, Jan R. Brentjens, +3

Journal of Clinical Investigation

Glomerular DiseaseRenal PathologyImmunologyRenal InflammationPathology +20

Murine interstitial nephritis. III. The selection of phenotypic (Lyt and L3T4) and idiotypic (RE-Id) T cell preferences by genes in Igh-1 and H-2K characterizes the cell-mediated potential for disease expression: susceptible mice provide a unique effector T cell repertoire in response to tubular antigen.

Eric G. Neilson, E McCafferty, Richard A. Mann, +2

The Journal of Immunology

T-regulatory CellImmunologyRenal InflammationPathologyImmunotherapy +17

Murine interstitial nephritis. IV. Long-term cultured L3T4+ T cell lines transfer delayed expression of disease as I-A-restricted inducers of the effector T cell repertoire.

Richard A. Mann, B Zakheim, Michael D. Clayman, +3

The Journal of Immunology

Kidney CapsuleDelayed ExpressionLymphocyte DevelopmentT-regulatory CellImmunology +19

Tubular antigen-derivatized cells induce a disease-protective, antigen-specific, and idiotype-specific suppressor T cell network restricted by I-J and Igh-V in mice with experimental interstitial nephritis.

Eric G. Neilson, E McCafferty, Richard A. Mann, +2

The Journal of Experimental Medicine

T-regulatory CellImmunologyImmune RegulationPathologyImmunologic Mechanism +16

Inhibitory role of dietary protein restriction on the development and expression of immune-mediated antitubular basement membrane-induced tubulointerstitial nephritis in rats.

David B. Agus, Richard A. Mann, David E. Cohn, +4

Journal of Clinical Investigation

Glomerular DiseaseLess DiseaseRenal PathologyImmunologyRenal Inflammation +17

Clonotypic heterogeneity in experimental interstitial nephritis. Restricted specificity of the anti-tubular basement membrane B cell repertoire is associated with a disease-modifying crossreactive idiotype.

Michael D. Clayman, M J Sun, L Michaud, +3

The Journal of Experimental Medicine

Glomerular DiseaseGene FamiliesLaboratory ImmunologyClonotypic HeterogeneityHumoral Response +18

The effects of daily cyclophosphamide administration on the development and extent of primary experimental interstitial nephritis in rats

David B. Agus, Richard A. Mann, Michael D. Clayman, +4

Kidney International

InflammationGlomerulonephritisRenal FunctionAutoimmune DiseaseMedicine +8

Murine interstitial nephritis. VI. Characterization of the B cell response in anti-tubular basement membrane disease.

Michael D. Clayman, L Michaud, Eric G. Neilson

The Journal of Immunology

B Cell ResponseRenal PathologyImmunologyRenal InflammationPathology +21