Theodore J. Detwiler

Metabolism-Directed Optimization of 3-Aminopyrazinone Acetamide Thrombin Inhibitors. Development of an Orally Bioavailable Series Containing P1 and P3 Pyridines

Christopher S. Burgey, Kyle A. Robinson, Terry A. Lyle et al. · Journal of Medicinal Chemistry · 2003 · 121 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Cyclopropylamino Acid Amide as a Pharmacophoric Replacement for 2,3-Diaminopyridine. Application to the Design of Novel Bradykinin B₁ Receptor Antagonists

Michael R. Wood, Kathy M. Schirripa, June J. Kim et al. · Journal of Medicinal Chemistry · 2006 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Effect of Calcitonin Gene-Related Peptide Receptor Antagonism on the Systemic Blood Pressure Responses to Mechanistically Diverse Vasomodulators in Conscious Rats

Joseph J. Lynch, Theodore J. Detwiler, Stefanie A. Kane et al. · Journal of Cardiovascular Pharmacology · 2010 · 24 citations

Medicine, Pharmacology, Physiology +16

An improved automated method to quantitate infarct volume in triphenyltetrazolium stained rat brain sections

Hillary Regan, Theodore J. Detwiler, Judy Huang et al. · Journal of Pharmacological and Toxicological Methods · 2007 · 16 citations

Medicine, Neurobiology, Neuroscience +10

Performance of biomarkers NF-L, NSE, Tau and GFAP in blood and cerebrospinal fluid in rat for the detection of nervous system injury

Kateřina Vlasáková, Takayuki Tsuchiya, Ivy Garfinkel et al. · Frontiers in Neuroscience · 2024 · 14 citations · Full text

Pharmacy, Pharmacology, Toxicology +17