Larissa M. Podust

Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from <i>Mycobacterium tuberculosis</i> in complex with azole inhibitors

Larissa M. Podust, T.L. Poulos, Michael R. Waterman · Proceedings of the National Academy of Sciences · 2001 · 515 citations · Full text

Crystal Structure, Drug Target, Molecular Biology +19

Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2

Bin Zhao, F. Peter Guengerich, Aouatef Bellamine et al. · Journal of Biological Chemistry · 2005 · 160 citations · Full text

The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 PikC from Streptomyces venezuelae

David H. Sherman, Shengying Li, Liudmila V. Yermalitskaya et al. · Journal of Biological Chemistry · 2006 · 146 citations · Full text

<i>Mycobacterium tuberculosis</i> CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest‐4‐en‐3‐one

Hugues Ouellet, Shenheng Guan, Jonathan B. Johnston et al. · Molecular Microbiology · 2010 · 134 citations · Full text

Medical Microbiology, Cholesterol Metabolism, Pulmonary Tuberculosis +13

Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations

Alison R. H. Narayan, Gonzalo Jiménez‐Osés, Peng Liu et al. · Nature Chemistry · 2015 · 133 citations

Molecular Dynamics, Engineering, Hydrogen Bond +9