Darrin D. Stuart

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

Meghna Das Thakur, Fernando Salangsang, Allison Landman et al. · Nature · 2013 · 735 citations

Medicine, Oncology, Pharmacology +16

Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

Guo Chen, Nitin Chakravarti, Kimberly Aardalen et al. · Clinical Cancer Research · 2014 · 212 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Phase I Dose-Escalation and -Expansion Study of the BRAF Inhibitor Encorafenib (LGX818) in Metastatic <i>BRAF</i> -Mutant Melanoma

Jean‐Pierre Delord, Caroline Robert, Marta Nyakas et al. · Clinical Cancer Research · 2017 · 192 citations · Full text

Medicine, Oncology, Pharmacology +17

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

Seth A. Ettenberg, Olga Charlat, Shanming Liu et al. · Proceedings of the National Academy of Sciences · 2010 · 153 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties

Yijun Gao, Matthew T. Chang, Daniel J. McKay et al. · Cancer Discovery · 2018 · 148 citations · Full text

Medicine, Cancer Biology, Oncology +17