Isaac D. Lutz

De novo design of high-affinity binders of bioactive helical peptides

Susana Vázquez Torres, Philip J. Y. Leung, Preetham Venkatesh et al. · Nature · 2023 · 224 citations · Full text

Life Sciences, Bioengineering, Molecular Biology +15

Top-down design of protein architectures with reinforcement learning

Isaac D. Lutz, Shunzhi Wang, Christoffer Norn et al. · Science · 2023 · 124 citations

Life Sciences, Bioengineering, Materials Science +17

Characterizing the portability of phage-encoded homologous recombination proteins

Gabriel Filsinger, Timothy M. Wannier, Felix Boel Pedersen et al. · Nature Chemical Biology · 2021 · 67 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy <i>in Vivo</i>

Lauren B. Crowe, Philip F. Hughes, David A. Alcorta et al. · ACS Chemical Biology · 2017 · 55 citations

Medicine, Molecular Biology, Oncology +17

De novo design of high-affinity protein binders to bioactive helical peptides

Susana Vázquez Torres, Philip J. Y. Leung, Isaac D. Lutz et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 22 citations · Full text

Engineering, Bioengineering, Bioinformatics +16