Philip J. Y. Leung

Robust deep learning–based protein sequence design using ProteinMPNN

Justas Dauparas, Ivan Anishchenko, Nathaniel R. Bennett et al. · Science · 2022 · 1.5K citations · Full text

Systems Biology, Engineering, Protein Designs +15

De novo design of high-affinity binders of bioactive helical peptides

Susana Vázquez Torres, Philip J. Y. Leung, Preetham Venkatesh et al. · Nature · 2023 · 194 citations · Full text

Robust deep learning based protein sequence design using ProteinMPNN

Justas Dauparas, Ivan Anishchenko, Nathaniel R. Bennett et al. · 2022 · 115 citations · Full text

Engineering, Structural Bioinformatics, Biomolecular Structure Prediction +16

Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics

Eric A. Nalefski, Nidhi Patel, Philip J. Y. Leung et al. · iScience · 2021 · 112 citations · Full text

Design of stimulus-responsive two-state hinge proteins

Florian Praetorius, Philip J. Y. Leung, Maxx H. Tessmer et al. · Science · 2023 · 79 citations · Full text