Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

Ignasi Morán, İldem Akerman, Martijn van de Bunt, +29

Cell Metabolism

Functional GenomicsDiabetesType 2Long Non-coding RnaAre Tissue-specific +7

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Sílvia Bonàs‐Guarch, Inês Cebola, +33

Nature Genetics

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks

İldem Akerman, Zhidong Tu, Anthony Beucher, +21

Cell Metabolism

Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury

Peter Arthur‐Farraj, Claire C. Morgan, Martyna Adamowicz, +7

Cell Reports

Dna MethylomeNeuroregenerationMolecular NeurosciencePeripheral Nerve InjuryNeural Stem Cell +10

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development

Josselin Soyer, Lydie Flasse, Wolfgang Raffelsberger, +8

Development

Transcriptional RegulationCell LineageDevelopmental BiologySignaling PathwayGut Endoderm +11

Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival

Georg Mellitzer, Anthony Beucher, Viviane Lobstein, +4

Journal of Clinical Investigation

Food IntakeGlucose HomeostasisCellular PhysiologyInsulin SignalingGastrointestinal Peptide Hormone +19

The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice

Anthony Beucher, Elisabet Gjernes, Caitlin Collin, +4

PLoS ONE

HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer

Mark Kalisz, Edgar Bernardo, Anthony Beucher, +16

The EMBO Journal

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Julie Piccand, Constance Vagne, Florence Blot, +17

Molecular Metabolism

The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

Anthony Beucher, Irene Miguel-Escalada, Diego Balboa, +10

Nature Cell Biology