Yuen‐Wai Ng

Group I and II mammalian PAKs have different modes of activation by Cdc42

Yohendran Baskaran, Yuen‐Wai Ng, Widyawilis Selamat et al. · EMBO Reports · 2012 · 109 citations · Full text

Molecular Physiology, Signal Transduction, Signaling Pathway +13

GIT1 Activates p21-Activated Kinase through a Mechanism Independent of p21 Binding

Tsui-Han Loo, Yuen‐Wai Ng, Louis Lim et al. · Molecular and Cellular Biology · 2004 · 88 citations · Full text

Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4 motif: evidence that nuclear paxillin promotes cell proliferation

Jingming Dong, Lei-Shong Lau, Yuen‐Wai Ng et al. · Biochemical Journal · 2008 · 76 citations

Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations

Yuen‐Wai Ng, Devanathan Raghunathan, Perry M. Chan et al. · Structure · 2010 · 41 citations · Full text

Biophysical Modeling, Signal Transduction, Protein Folding +10

Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination

I. Acosta-Colman, Serge Urbach, Anne Doye et al. · Scientific Reports · 2018 · 23 citations · Full text