Xavier Gómez‐Santacana

An allosteric modulator to control endogenous G protein-coupled receptors with light

Silvia Pittolo, Xavier Gómez‐Santacana, Kay Eckelt et al. · Nature Chemical Biology · 2014 · 183 citations · Full text

Photoreceptor Cell, Molecular Physiology, Signal Transduction +11

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

Xavier Gómez‐Santacana, Silvia Pittolo, Xavier Rovira et al. · ACS Central Science · 2016 · 79 citations · Full text

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4

Charleine Zussy, Xavier Gómez‐Santacana, Xavier Rovira et al. · Molecular Psychiatry · 2016 · 75 citations · Full text

Optogenetics, Neurophysiology, Pain Medicine +14

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

Chady Nasrallah, Giuseppe Cannone, Julie Briot et al. · Cell Reports · 2021 · 61 citations · Full text

Photoswitching the Efficacy of a Small‐Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism

Xavier Gómez‐Santacana, Sabrina M. de Munnik, Prashanna Vijayachandran et al. · Angewandte Chemie International Edition · 2018 · 46 citations · Full text