Kazuyo Sugiyama

UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G2 checkpoint abrogation

Kazuyo Sugiyama, Makiko Shimizu, Tadakazu Akiyama et al. · International Journal of Cancer · 2000 · 89 citations

Chemoprevention Strategy, Apoptosis, Cell Death +18

Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).

Kazuyo Sugiyama, Tadakazu Akiyama, Makiko Shimizu et al. · PubMed · 1999 · 35 citations

Cell Death, Cell Cycle, Metronomic Chemotherapy +16

G1–checkpoint Function Including a Cyclin‐dependent Kinase 2 Regulatory Pathway as Potential Determinant of 7–Hydroxystaurosporine (UCN‐01)‐induced Apoptosis and G1–phase Accumulation

Tadakazu Akiyama, Kazuyo Sugiyama, Makiko Shimizu et al. · Japanese Journal of Cancer Research · 1999 · 24 citations · Full text

Apoptosis, G1–checkpoint Function, Cell Death +23

Combined effect of navelbine with medroxyprogesterone acetate against human breast carcinoma MCF-7 cells in vitro

Kazuyo Sugiyama, M. Shimizu, Tomoko Akiyama et al. · British Journal of Cancer · 1998 · 16 citations · Full text

Medroxyprogesterone Acetate, Breast Oncology, Oncology +10