Pedro Blecua

Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response

Rajarsi Mandal, Robert Samstein, Ken-Wing Lee et al. · Science · 2019 · 564 citations · Full text

Immunodeficiencies, Immunology, Pathology +16

Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes

Ian Ganly, Vladimir Makarov, Shyamprasad Vasudeva Deraje et al. · Cancer Cell · 2018 · 273 citations · Full text

Recurrent Mitochondrial Mutations, Unique Chromosomal Landscapes, Somatic Variant +6

Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S <i>BTK</i> Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell Lymphoma

David Chiron, Maurizio Di Liberto, Peter Martin et al. · Cancer Discovery · 2014 · 271 citations · Full text

Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes

Nadeem Riaz, Pedro Blecua, Raymond S. Lim et al. · Nature Communications · 2017 · 252 citations · Full text

Genetics, Pathology, Pan-cancer Analysis +16

Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy

Robert Samstein, Chirag Krishna, Xiaoxiao Ma et al. · Nature Cancer · 2020 · 192 citations · Full text

Cancer Immunosurveillance, Medicine, Immunology +9