Chirag Krishna

Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response

Rajarsi Mandal, Robert Samstein, Ken-Wing Lee et al. · Science · 2019 · 564 citations · Full text

Immunodeficiencies, Immunology, Pathology +16

ILC1 Confer Early Host Protection at Initial Sites of Viral Infection

Orr-El Weizman, Nicholas M. Adams, Iona S. Schuster et al. · Cell · 2017 · 433 citations · Full text

Host Response, Host Factor, Viral Persistence +10

Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

Chirag Krishna, Renzo G. DiNatale, Fengshen Kuo et al. · Cancer Cell · 2021 · 408 citations · Full text

Therapy Efficacy, Cancer Immunosurveillance, T-regulatory Cell +11

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Wei Yang, Ken-Wing Lee, Raghvendra M. Srivastava et al. · Nature Medicine · 2019 · 371 citations

Autoimmune Disease, Adaptive Immune System, T-regulatory Cell +10

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

Diego Chowell, Chirag Krishna, Federica Pierini et al. · Nature Medicine · 2019 · 303 citations · Full text

Hla, Histocompatibility, Immunogenetics +13