Mallareddy Komandla

Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton’s Tyrosine Kinase

Christopher R. Smith, Douglas R. Dougan, Mallareddy Komandla et al. · Journal of Medicinal Chemistry · 2015 · 73 citations · Full text

Drug Target, Bioorganic Chemistry, Tyrosine Kinase +18

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2

Christopher M. McBride, Zacharia S. Cheruvallath, Mallareddy Komandla et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 24 citations · Full text

Drug Target, Engineering, Drug Design +9

Structure–activity relationships of novel, highly potent, selective, and orally active CCR1 antagonists

Yun Feng Xie, Kirk Lake, Kathleen Ligsay et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 18 citations · Full text

Biochemistry, Medicine, Active Ccr1 Antagonists +6

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1

Zacharia S. Cheruvallath, Mingnam Tang, Christopher M. McBride et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 16 citations · Full text

Drug Target, Engineering, Drug Design +9

Identification of novel series of human CCR1 antagonists

Yun Feng Xie, Ila Sircar, Kirk Lake et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 14 citations · Full text

Human Ccr1 Antagonists, G Protein-coupled Receptor, Medicine +5