Ganesh R. Manjeri

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations · Full text

Microbial Pathogens, Trained Immunity, Innate Immune System +25

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Shih‐Chin Cheng, Brendon P. Scicluna, Rob J.W. Arts et al. · Nature Immunology · 2016 · 587 citations

Inflammation, Energy Metabolism, Granulocyte +11

Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V

Marleen Forkink, Ganesh R. Manjeri, Dania C. Liemburg-Apers et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2014 · 106 citations · Full text

Mitochondrial Hyperpolarization, Signal Transduction, Biochemistry +8

Skeletal muscle mitochondria of NDUFS4−/− mice display normal maximal pyruvate oxidation and ATP production

Mohammad Tauqeer Alam, Ganesh R. Manjeri, Richard J. Rodenburg et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2015 · 30 citations · Full text

Energy Metabolism, Mitochondrial Function, Biochemistry +14

Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia

Ganesh R. Manjeri, Richard J. Rodenburg, Lionel Blanchet et al. · Journal of Inherited Metabolic Disease · 2015 · 13 citations · Full text

Isoflurane Anesthesia, Healthy Mice, Mac Isoflurane +16