Chunyang Jin

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance

David Westover, Xiang Ling, Hong Lam et al. · Molecular Cancer · 2015 · 71 citations · Full text

Medicine, Oncology, Pharmacology +12

A generative deep learning approach to de novo antibiotic design

Aarti Krishnan, Melis N. Anahtar, Jacqueline A. Valeri et al. · Cell · 2025 · 63 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +9

Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase

Lulu Jiang, Xuefei Wu, Shuo Wang et al. · Journal of Neuroinflammation · 2016 · 51 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Synthesis, Pharmacological Characterization, and Structure–Activity Relationship Studies of Small Molecular Agonists for the Orphan GPR88 Receptor

Chunyang Jin, Ann M. Decker, Xi‐Ping Huang et al. · ACS Chemical Neuroscience · 2014 · 48 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14

Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake

Chunyang Jin, Ann M. Decker, Viren H. Makhijani et al. · Journal of Medicinal Chemistry · 2018 · 47 citations · Full text

Medicine, Neuroscience, Pharmacology +17