A prognostic neural epigenetic signature in high-grade glioma

Richard Drexler, Robin Khatri, Thomas Sauvigny, +42

Nature Medicine

Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma

Philip Schmassmann, Julien Roux, Alicia Buck, +15

Science Translational Medicine

Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis

Beatrix Schoenhacker‐Alte, Thomas Mohr, Christine Pirker, +10

Cancer Letters

Molecular PhysiologySignal TransductionEr HomeostasisApoptosis InductionSignaling Pathway +8

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity

Sohyon Lee, Marcel Bühler, Julien Mena, +21

Nature Medicine

Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects

Yufei Wang, Alicia Buck, Brandon Piel, +25

Molecular Cancer

DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils

Alicia Buck, Felix P. Sanchez Klose, Vignesh Venkatakrishnan, +4

ImmunoHorizons

Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model

Yufei Wang, Alicia Buck, Marion Grimaud, +14

Molecular Therapy — Oncolytics

Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker

Tomás A. Martins, Deniz Kaymak, Nazanin Tatari, +23

Nature Communications

In Vivo Transmigrated Human Neutrophils Are Highly Primed for Intracellular Radical Production Induced by Monosodium Urate Crystals

Lisa Davidsson, Agnes Dahlstrand Rudin, Felix P. Sanchez Klose, +4

International Journal of Molecular Sciences

Lung InflammationImmunologyInnate ImmunityRedox BiologyOxidative Stress +17

Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model

Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, +16

iScience