Peter D. Gorycki

Pyrimidinylimidazole inhibitors of CSBP/P38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes

Jerry L. Adams, Jeffrey C. Boehm, Shouki Kassis et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 113 citations · Full text

Biochemistry, Medicine, Liver Physiology +8

SB 207499 (Ariflo), a second generation phosphodiesterase 4 inhibitor, reduces tumor necrosis factor alpha and interleukin-4 production in vivo.

Don E. Griswold, Edward F. Webb, Alison M. Badger et al. · PubMed · 1998 · 86 citations

Inflammation, Cytokine, Anti-inflammatory +13

Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer

Yanli Deng, Caroline Sychterz, A. Benjamin Suttle et al. · Xenobiotica · 2012 · 83 citations

Antiasthmatic Activity of the Second-Generation Phosphodiesterase 4 (PDE4) Inhibitor SB 207499 (Ariflo) in the Guinea Pig

David C. Underwood, Steven Bochnowicz, Ruth R. Osborn et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 70 citations

Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects

Yanli Deng, Armina Madatian, Mary Beth Wire et al. · Drug Metabolism and Disposition · 2011 · 54 citations