Mary C. Casey

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H

Jayakanth Kankanala, Karen A. Kirby, Andrew D. Huber et al. · European Journal of Medicinal Chemistry · 2017 · 45 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity

Sanjeev Kumar V. Vernekar, Jing Tang, Bulan Wu et al. · Journal of Medicinal Chemistry · 2017 · 43 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

3-Hydroxypyrimidine-2,4-dione-5-<i>N</i>-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H

Bulan Wu, Jing Tang, Daniel J. Wilson et al. · Journal of Medicinal Chemistry · 2016 · 42 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity

Lei Wang, Jing Tang, Andrew D. Huber et al. · European Journal of Medicinal Chemistry · 2018 · 34 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +14

Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability

Lei Wang, Mary C. Casey, Sanjeev Kumar V. Vernekar et al. · Acta Pharmaceutica Sinica B · 2020 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17