Florent Alix

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of <i>N-</i>Hydroxysuccinimidyl Formate as CO Surrogate

Anaïs Barré, Mihaela-Liliana Ţînţaş, Florent Alix et al. · The Journal of Organic Chemistry · 2015 · 31 citations

Asymmetric Catalysis, Cross-coupling Reaction, Novel Organocatalysts +12

Dihydroquinoline Carbamate Derivatives as “Bio-oxidizable” Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation

Pierre Bohn, Fabienne Gourand, Cyril Papamicaël et al. · ACS Chemical Neuroscience · 2015 · 29 citations

Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies

Mihaela-Liliana Ţînţaş, Vincent Gembus, Florent Alix et al. · European Journal of Medicinal Chemistry · 2018 · 16 citations · Full text

Molecular Docking, Medicinal Chemistry, Pharmaceutical Science +12

Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile

Florent Alix, Vincent Gembus, Laurent Coquet et al. · ACS Omega · 2018 · 10 citations · Full text