Francine Z. Chen

Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Deryk Loo, Ralph Alderson, Francine Z. Chen et al. · Clinical Cancer Research · 2012 · 280 citations

Pharmacy, Immunology, Oncology +17

Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer

Juniper A. Scribner, Jennifer G. Brown, Thomas Son et al. · Molecular Cancer Therapeutics · 2020 · 159 citations

Medicine, Medicinal Chemistry, Oncology +15

The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial

Jason J. Luke, Manish R. Patel, George R. Blumenschein et al. · Nature Medicine · 2023 · 128 citations · Full text

Medicine, Oncology, Pharmacology +17

Development of MGD007, a gpA33 x CD3-Bispecific DART Protein for T-Cell Immunotherapy of Metastatic Colorectal Cancer

Paul A. Moore, Kalpana Shah, Yinhua Yang et al. · Molecular Cancer Therapeutics · 2018 · 76 citations

Medicine, Immunology, Oncology +17

Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody–drug Conjugate Targeting ADAM9-expressing Tumors

Juniper A. Scribner, Stuart W. Hicks, Kerstin W. Sinkevicius et al. · Molecular Cancer Therapeutics · 2022 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17