P Humphreys

Impaired Processing of Prohormones Associated with Abnormalities of Glucose Homeostasis and Adrenal Function

Stephen O’Rahilly, Helen Gray, P Humphreys et al. · New England Journal of Medicine · 1995 · 241 citations · Full text

Medicine, Endocrinology, Molecular Genetics +17

Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance.

Karim Dib, Jonathan P. Whitehead, P Humphreys et al. · Journal of Clinical Investigation · 1998 · 56 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Chromosome 4q Locus Associated With Insulin Resistance in Pima Indians: Studies in Three European NIDDM Populations

P Humphreys, Mark I. McCarthy, Jaakko Tuomilehto et al. · Diabetes · 1994 · 47 citations

Medicine, Endocrinology, Genetics +9

Molecular scanning of the insulin receptor substrate 1 gene in subjects with severe insulin resistance: detection and functional analysis of a naturally occurring mutation in a YMXM motif.

Jonathan P. Whitehead, P Humphreys, Anna Krook et al. · Diabetes · 1998 · 39 citations

Life Sciences, Genetics, Molecular Biology +7

Severe insulin resistance, diabetes mellitus, hypertriglyceridemia, and pseudoacromegaly.

Sudhesh Kumar, P.N. Durrington, Stephen O’Rahilly et al. · The Journal of Clinical Endocrinology & Metabolism · 1996 · 26 citations · Full text

Medicine, Endocrinology, Internal Medicine +11