ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles

Wonhyo Seo, Yanhang Gao, Yong He, +15

Journal of Hepatology

Aldh2 DeficiencyAldehyde DehydrogenaseOncogenic PathwaysOncogenic AgentLiver Physiology +7

Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice

Xiaogang Xiang, Dechun Feng, Seonghwan Hwang, +12

Journal of Hepatology

InflammationImpaired Regeneration PathwaysCytokineDevelopmental BiologyHepatology +11

Interleukin‐22 Ameliorates Neutrophil‐Driven Nonalcoholic Steatohepatitis Through Multiple Targets

Seonghwan Hwang, Yong He, Xiaogang Xiang, +9

Hepatology

Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene

Zehua Zhao, Zixuan Wang, Da Zhou, +19

Cellular and Molecular Gastroenterology and Hepatology

Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking

Adrien Guillot, Tianyi Ren, Tony Jourdan, +6

Proceedings of the National Academy of Sciences

Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids

Yanhang Gao, Zhou Zhou, Tianyi Ren, +18

Gut

Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms

Jing Ma, Haixia Cao, Robim M. Rodrigues, +10

JCI Insight

Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes

Yong He, Dechun Feng, Seonghwan Hwang, +11

Journal of Hepatology

InflammationInterleukin-20 ExacerbatesCytokineHepatologyBacterial Infection +9

Distribution and Antimicrobial Resistance of Salmonella Isolated from Pigs with Diarrhea in China

Jin-Hui Su, Yaohong Zhu, Tianyi Ren, +4

Microorganisms

Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China

Tianyi Ren, Huan Wang, Ruihong Wu, +1

Gastroenterology Research and Practice