Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles

Marianna Yanez Arteta, Tomas Kjellman, Stefano Bartesaghi, +8

Proceedings of the National Academy of Sciences

Ethylene GlycolEngineeringLipid NanoparticlesMolecular BiologyGene Delivery +14

Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells

Marco Maugeri, Muhammad Nawaz, Alexandros Papadimitriou, +15

Nature Communications

Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles

Federica Sebastiani, Marianna Yanez Arteta, Michael Lerche, +14

ACS Nano

Identification of RNA-binding proteins in exosomes capable of interacting with different types of RNA: RBP-facilitated transport of RNAs into exosomes

Luisa Statello, Marco Maugeri, Elena Garré, +12

PLoS ONE

Nucleation and crystal growth in supersaturated solutions of a model drug

Lennart Lindfors, Sara Forssén, Jan Westergren, +1

Journal of Colloid and Interface Science

EngineeringSolution (Chemistry)NucleationCrystallographyChemistry +5

Amorphous Drug Nanosuspensions. 1. Inhibition of Ostwald Ripening

Lennart Lindfors, Pia Skantze, Urban Skantze, +3

Langmuir

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale

Prasath Paramasivam, Christian Franke, Martin Stöter, +11

The Journal of Cell Biology

Endosomal EscapeImmunologyLipid NanoparticlesMolecular BiologyExtracellular Microvesicles +15

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: Application of the mechanistic absorption model GI-Sim

Erik Sjögren, Jan Westergren, Iain Grant, +5

European Journal of Pharmaceutical Sciences

Gastrointestinal Drug AbsorptionGastrointestinal PharmacologyMedicineBioanalysisGastroenterology +9

Predicting Intestinal Precipitation—A Case Example for a Basic BCS Class II Drug

Sara Carlert, Anna Pålsson, Gunilla Hanisch, +5

Pharmaceutical Research

Pharmacokinetic ModelingGastrointestinal PharmacologyPharmacologyGastroenterologyClinical Gastroenterology +4

Amorphous Drug Nanosuspensions. 3. Particle Dissolution and Crystal Growth

Lennart Lindfors, Pia Skantze, Urban Skantze, +2

Langmuir