COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis

Masashi Okamura, Hiromi Kudo, Ken‐ichi Wakabayashi, +13

Proceedings of the National Academy of Sciences

Transcriptional RegulationSignaling PathwayLocal ChromatinPparγ Gene ExpressionMetabolic Signaling +16

SOX6 Suppresses Cyclin D1 Promoter Activity by Interacting with β-Catenin and Histone Deacetylase 1, and Its Down-regulation Induces Pancreatic β-Cell Proliferation

Haruhisa Iguchi, Yasuyo Urashima, Yosuke Inagaki, +7

Journal of Biological Chemistry

Cooperative Interaction between Hepatocyte Nuclear Factor 4 <i>α</i> and GATA Transcription Factors Regulates ATP-Binding Cassette Sterol Transporters ABCG5 and ABCG8

Koichi Sumi, Toshiya Tanaka, Aoi Uchida, +19

Molecular and Cellular Biology

Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

Yohei Abe, Yosuke Fujiwara, Hiroki Takahashi, +14

Nature Communications

SOX6 Attenuates Glucose-stimulated Insulin Secretion by Repressing PDX1 Transcriptional Actvity and Is Down-regulated in Hyperinsulinemic Obese Mice

Haruhisa Iguchi, Yukio Ikeda, Masashi Okamura, +20

Journal of Biological Chemistry

YF476 is a new potent and selective gastrin/cholecystokinin‐B receptor antagonist <i>in vitro</i> and <i>in vivo</i>

Yusuke Takinami, Hidenobu Yuki, Akito Nishida, +7

Alimentary Pharmacology & Therapeutics

Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors

Kenji Hirate, Aoi Uchida, Yuki Ogawa, +2

Neuroscience Research

InflammationAnti-inflammatoryNon-steroidal Anti-inflammatory DrugMedicinePain Medicine +10

Hepatocyte Nuclear Factor 4α Contributes to Thyroid Hormone Homeostasis by Cooperatively Regulating the Type 1 Iodothyronine Deiodinase Gene with GATA4 and Krüppel-Like Transcription Factor 9

Hiroto Ohguchi, Toshiya Tanaka, Aoi Uchida, +13

Molecular and Cellular Biology

GeneticsOxidative StressType 1Transcriptional RegulationHormone Homeostasis +17

Spatiotemporal dynamics of SETD5-containing NCoR–HDAC3 complex determines enhancer activation for adipogenesis

Yoshihiro Matsumura, Ryo Ito, Ayumu Yajima, +27

Nature Communications

Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease

Ryo Ito, Shiyu Xie, Myagmar Tumenjargal, +24

iScience