Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Ingrid G. Winkler, Natalie A. Sims, Allison R. Pettit, +8

Blood

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

Ingrid G. Winkler, Valérie Barbier, Bianca Nowlan, +5

Nature Medicine

Lineage PlasticityCell LineageDevelopmental BiologyVascular Niche E-selectinMedicine +8

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation

Ingrid G. Winkler, Allison R. Pettit, Liza J. Raggatt, +8

Leukemia

Hematopoietic Stem CellBone Marrow FailureAgents G-csfMedicineStem Cell Mobilization +9

Hematopoietic Progenitor Cell Mobilization Results in Hypoxia with Increased Hypoxia-Inducible Transcription Factor-1α and Vascular Endothelial Growth Factor A in Bone Marrow

Jean-Pierre Lévesque, Ingrid G. Winkler, Jean Hendy, +5

Stem Cells

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation

Catherine E. Forristal, Ingrid G. Winkler, Bianca Nowlan, +3

Blood

Engineering a humanized bone organ model in mice to study bone metastases

Laure C Martine, Boris Michael Holzapfel, Jacqui McGovern, +19

Nature Protocols

Regenerative MedicineTissue EngineeringXenotransplantationEngineeringBone Morphogenic Protein +9

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2

Faith H. Brennan, Trisha Jogia, Ellen R. Gillespie, +13

JCI Insight

ImmunologyImmune RegulationCell DeathRapid MobilizationInjured Spinal Cord +19

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse

Rebecca Jacobsen, Catherine E. Forristal, Liza J. Raggatt, +7

Experimental Hematology

InflammationGranulocyteStem Cell MobilizationImmunologyHematology +5

Tissue engineered humanized bone supports human hematopoiesis in vivo

Boris Michael Holzapfel, Dietmar W. Hutmacher, Bianca Nowlan, +10

Biomaterials

Regenerative MedicineTissue EngineeringEngineeringMedicineStem Cell Mobilization +6

Control of Metastases via Myeloid CD39 and NK Cell Effector Function

Juming Yan, Xian-Yang Li, Amelia Roman Aguilera, +9

Cancer Immunology Research