Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism

Katherine N. Theken, Yangmei Deng, M. Alison Kannon, +3

Drug Metabolism and Disposition

The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

Robert N. Schuck, Weibin Zha, Matthew L. Edin, +13

PLoS ONE

PathologyFatty Liver DiseaseOxidative StressInflammationMetabolic Syndrome +16

Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury

Hao Liu, Wenjin Li, Muzamil Ahmad, +7

Neurobiology of Disease

InflammationUbiquitin-c-terminal Hydrolase-l1Reductive StressBiochemistryRedox Regulator +9

Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest

Philip E. Empey, Tricia M. Miller, Ashley Philbrick, +3

Critical Care Medicine

Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance

Wojciech G. Garbacz, Peipei Lu, Tricia M. Miller, +6

Molecular and Cellular Biology

PathologyFatty Liver DiseaseGlucose ToleranceInsulin SignalingObesity +19

Enalapril reverses high-fat diet-induced alterations in cytochrome P450-mediated eicosanoid metabolism

Katherine N. Theken, Yangmei Deng, Robert N. Schuck, +5

American Journal of Physiology-Endocrinology and Metabolism

Metabolic DisorderCyp EpoxygenaseLipid PeroxidationOxidative StressInflammation +16

Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain

Tricia M. Miller, Mark Donnelly, Elizabeth Crago, +4

Journal of Chromatography B

MedicineArachidonic AcidHuman CsfLipid PeroxidationMetabolomic Profiling +9

Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites

Hao Liu, Wenjin Li, Marie E. Rose, +5

NeuroToxicology

NeuropeptidesBioactive Cyclopentenone MetabolitesMedicinePhysiologyCell Death +8

Increased Generation of Cyclopentenone Prostaglandins after Brain Ischemia and Their Role in Aggregation of Ubiquitinated Proteins in Neurons

Hao Liu, Wenjin Li, Muzamil Ahmad, +8

Neurotoxicity Research

Cyclopentenone ProstaglandinsUbiquitinated ProteinsNeurophysiologyMedicineNeuropharmacology +13

Rapid and simultaneous quantitation of prostanoids by UPLC–MS/MS in rat brain

Jafar Sadik Shaik, Tricia M. Miller, Steven H. Graham, +2

Journal of Chromatography B

NeurophysiologyMedicineNeuropharmacologyExperimental PharmacologyNeuroscience +8