Tanshinone II A attenuates inflammatory responses of rats with myocardial infarction by reducing MCP-1 expression

Zhiguang Ren, Yinghui Tong, Wei Xu, +2

Phytomedicine

InflammationAnti-inflammatoryCardiovascular DiseaseAtherosclerosisMedicine +9

New Use for an Old Drug: Inhibiting ABCG2 with Sorafenib

Yinxiang Wei, Yuanfang Ma, Qing Zhao, +4

Molecular Cancer Therapeutics

Drug TargetChemoprevention StrategyPharmacotherapyTumor BiologyDrug Resistance +16

Synthesis and biological evaluation of bifendate–chalcone hybrids as a new class of potential P-glycoprotein inhibitors

Xiaoke Gu, Zhiguang Ren, Xiaobo Tang, +5

Bioorganic & Medicinal Chemistry

Potential P-glycoprotein InhibitorsBiochemistryMedicineNew ClassPharmacotherapy +5

Anticancer efficacy of a nitric oxide‐modified derivative of bifendate against multidrug‐resistant cancer cells

Zhiguang Ren, Xiaoke Gu, Bin Lü, +6

Journal of Cellular and Molecular Medicine

Potent Inhibition of Nitric Oxide-Releasing Bifendate Derivatives against Drug-Resistant K562/A02 Cells in Vitro and in Vivo

Xiaoke Gu, Zhangjian Huang, Zhiguang Ren, +8

Journal of Medicinal Chemistry

Nitric OxideBifendate DerivativesPharmacotherapyExperimental PharmacologyPharmaceutical Chemistry +15

Synthesis and biological evaluation of novel bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potent P-glycoprotein inhibitors

Xiaoke Gu, Zhiguang Ren, Xiaobo Tang, +5

European Journal of Medicinal Chemistry

Derivative (Chemistry)BiochemistryPotent P-glycoprotein InhibitorsMedicineNovel Bifendate Derivatives +6

Rapid emergence of a PB2-E627K substitution confers a virulent phenotype to an H9N2 avian influenza virus during adaption in mice

Xiaoyu Sang, Airong Wang, Tongjie Chai, +16

Archives of Virology

Viral EvolutionMedicinePathogenesisViral PathogenesisMolecular Biology +5

H5N1 influenza virus-like particle vaccine protects mice from heterologous virus challenge better than whole inactivated virus

Zhiguang Ren, Xianliang Ji, Lingnan Meng, +13

Virus Research

VaccinationVaccine DevelopmentHeterologous Virus ChallengeImmunologyVirus-like Particle Vaccine +6

Fragment-Based Approaches Identified Tecovirimat-Competitive Novel Drug Candidate for Targeting the F13 Protein of the Monkeypox Virus

Yasir Ali, Hina Imtiaz, Tahir Muhammad, +6

Viruses

Tumour necrosis factor‐α‐induced protein 8‐like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells

Dongdong Wu, Shiyu Liu, Ying‐Ran Gao, +14

Journal of Cellular and Molecular Medicine