Sarah E. LeBoeuf

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

Rodrigo Romero, Volkan I. Sayin, Shawn M. Davidson et al. · Nature Medicine · 2017 · 640 citations · Full text

Tumor Biology, Medicine, Kras-driven Lung Cancer +11

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1

Luca Lignitto, Sarah E. LeBoeuf, Harrison Homer et al. · Cell · 2019 · 591 citations · Full text

Tumor Biology, Oncogenic Agent, Medicine +7

Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression

Antonio F. Santidrián, Akemi Matsuno‐Yagi, Melissa Ritland et al. · Journal of Clinical Investigation · 2013 · 419 citations · Full text

Nad+/nadh Balance, Breast Oncology, Mitochondrial Function +11

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

Volkan I. Sayin, Sarah E. LeBoeuf, Simranjit X. Singh et al. · eLife · 2017 · 224 citations · Full text

Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

Sarah E. LeBoeuf, Warren Wu, Triantafyllia Karakousi et al. · Cell Metabolism · 2019 · 151 citations · Full text

Reductive Stress, Biochemistry, Medicine +8