Izortze Santín

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Décio L. Eizirik, Michael Sammeth, Thomas Bouckenooghe et al. · PLoS Genetics · 2012 · 472 citations · Full text

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

Miriam Cnop, Baroj Abdulkarim, Guy Bottu et al. · Diabetes · 2013 · 258 citations · Full text

Genetics, Cell Death, Transcriptomics Technology +21

Epigenetic Defects of<i>GNAS</i>in Patients with Pseudohypoparathyroidism and Mild Features of Albright’s Hereditary Osteodystrophy

Guiomar Pérez de Nanclares, Eduardo Fernández‐Rebollo, Izortze Santín et al. · The Journal of Clinical Endocrinology & Metabolism · 2007 · 160 citations · Full text

<i>PTPN2</i>, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

Izortze Santín, Fabrice Moore, Máikel L. Colli et al. · Diabetes · 2011 · 142 citations · Full text

<i>TYK2</i>, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

Laura Marroquí, Reinaldo S. Dos Santos, Tina Fløyel et al. · Diabetes · 2015 · 119 citations

Modulates Apoptosis, Mhc Class, Immunology +18