Matsuhiko Hayashi

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

Hiroyuki Unoki‐Kubota, Atsushi Takahashi, Takahisa Kawaguchi et al. · Nature Genetics · 2008 · 721 citations

Metabolic Syndrome, Genetic Determinant, Diabetes Epidemiology +10

Inhibition of diabetic nephropathy by a decoy peptide corresponding to the “handle” region for nonproteolytic activation of prorenin

Atsuhiro Ichihara, Matsuhiko Hayashi, Yuki Kaneshiro et al. · Journal of Clinical Investigation · 2004 · 436 citations

Peptide Therapeutics, Gastrointestinal Peptide Hormone, Renal Function +18

Prorenin Receptor Blockade Inhibits Development of Glomerulosclerosis in Diabetic Angiotensin II Type 1a Receptor–Deficient Mice

Atsuhiro Ichihara, Fumiaki Suzuki, Tsutomu Nakagawa et al. · Journal of the American Society of Nephrology · 2006 · 284 citations

Hypertension, Immunology, Mapk Activation Signal +16

Nonproteolytic Activation of Prorenin Contributes to Development of Cardiac Fibrosis in Genetic Hypertension

Atsuhiro Ichihara, Yuki Kaneshiro, Tomoko Takemitsu et al. · Hypertension · 2006 · 263 citations · Full text

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

Koshu Okubo, Miho Kurosawa, Mako Kamiya et al. · Nature Medicine · 2018 · 220 citations

Inflammation, Cell Signaling, Immunology +11