Lucas A. Horn

Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models

Sarah Greene, Yvette Robbins, Wojciech K. Mydlarz et al. · Clinical Cancer Research · 2019 · 263 citations · Full text

HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells

Katherine H. Parker, Pratima Sinha, Lucas A. Horn et al. · Cancer Research · 2014 · 242 citations · Full text

Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy

Lillian Sun, Paúl E. Clavijo, Yvette Robbins et al. · JCI Insight · 2019 · 228 citations · Full text

Myeloid-derived Suppressor Cell, T-regulatory Cell, Immunology +18

Combined <i>MYC</i> Activation and <i>Pten</i> Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer

Gretchen K. Hubbard, Laura N. Mutton, May Khalili et al. · Cancer Research · 2015 · 125 citations · Full text

Transcriptional Regulation, Radiation Oncology, Genetic Instability +15

Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1–mediated tumor eradication

Lucas A. Horn, Paul L. Chariou, Sofia R. Gameiro et al. · Journal of Clinical Investigation · 2022 · 113 citations · Full text

Tumor Collagenous Matrix, Immunology, Immune Regulation +20