Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

Xingnan Zheng, Bo Zhai, Peppi Koivunen, +21

Genes & Development

Molecular BiologyChemical BiologyFoxo Transcription FactorsEnzymatic ModificationRedox Biology +17

Regulatory B cells contribute to the impaired antitumor immunity in ovarian cancer patients

Xin Wei, Yangqiu Jin, Yinpu Tian, +4

Tumor Biology

Sequence analysis and expression differentiation of chemokine receptor CXCR4b among three populations of Megalobrama amblycephala

Jie Zhang, Xin Wei, Li Ping Chen, +4

Developmental & Comparative Immunology

Signal TransductionChemokine Receptor Cxcr4bImmunologySequence AnalysisExpression Differentiation +2

Molecular characterization and expression analysis of three hypoxia-inducible factor alpha subunits, HIF-1α/2α/3α of the hypoxia-sensitive freshwater species, Chinese sucker

Nan Chen, Li Ping Chen, Jie Zhang, +5

Gene

BiologyHypoxia-sensitive Freshwater SpeciesExpression AnalysisRedox RegulatorPhysiology +5

Discovery of siRNA Lipid Nanoparticles to Transfect Suspension Leukemia Cells and Provide In Vivo Delivery Capability

Wei He, Malcolm J. Bennett, Leopoldo Luistro, +10

Molecular Therapy

A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing

Cui Liu, Yanbao Yu, Feng Liu, +6

Nature Communications

Histone ModificationsChromatinSystems BiologyGene-specific SilencingChromatin Remodeling +12

Proteomic profiling identifies signatures associated with progression of precancerous gastric lesions and risk of early gastric cancer

Xue Li, Linheng Wang, Zhongwu Li, +24

EBioMedicine

Nobiletin alleviates endometriosis via down-regulating NF-κB activity in endometriosis mouse model

Xin Wei, Xu Shao

Bioscience Reports

FOXP1 enhances fibrosis via activating Wnt/β-catenin signaling pathway in endometriosis.

Xu Shao, Xin Wei

PubMed

Transcriptional RegulationFibrosisUterine FibroidsCollagen ContractionBone Morphogenic Protein +12

A genomic mutation signature predicts the clinical outcomes of immunotherapy and characterizes immunophenotypes in gastrointestinal cancer

Xi Jiao, Xin Wei, Shuang Li, +15

npj Precision Oncology