Flavonoids derived from licorice suppress LPS-induced acute lung injury in mice by inhibiting the cGAS-STING signaling pathway

Jincai Wen, Shuanglin Qin, Yurong Li, +13

Food and Chemical Toxicology

InflammationAcute Lung InjuryAnti-inflammatoryInflammatory Lung DiseaseRespiratory Toxicology +7

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway

Xiaohe Li, Cheng Lu, Shuangwei Liu, +23

European Journal of Medicinal Chemistry

FibrosisLung InflammationIdiopathic Pulmonary FibrosisPharmacologyPathology +6

Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases

Yan Wang, Shuanglin Qin, Huanying Zhao, +11

Phytomedicine

InflammationAnti-inflammatorySignal TransductionAutoimmune DiseaseInflammatory Disease +10

Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids

Xinhua Liu, Benlong Li, Zhen Zhang, +7

Journal of Medicinal Chemistry

Natural Triterpenoic AcidsMedicinal ChemistryNatural Product SynthesisPharmaceutical ChemistryMedicine +13

Synthesis of aziridines with multiple chiral substitutions by copper-catalyzed diastereoselective radical aminotrifluoromethylation of alkenes

Shuanglin Qin, Linbin Yao, Yunhao Luo, +8

Organic Chemistry Frontiers

One-step CatalyticEngineeringAlkene MetathesisOrganic ChemistryMultiple Chiral Substitutions +8

Network pharmacology-based strategy for predicting therapy targets of Ecliptae Herba on breast cancer

Hui Li, Wei Shi, Tingming Shen, +6

Medicine

Tumor BiologyEcliptae HerbaBreast OncologyChemoprevention StrategyMedicine +13

A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway

Shuangwei Liu, Xian Gao, Lisong Zhang, +15

European Journal of Medicinal Chemistry

Novel TherapyMedicinePharmacologyStem Cell ResearchStem-cell Therapy +8

LicochalconeB inhibits cGAS-STING signaling pathway and prevents autoimmunity diseases

Wei Luo, Song Zheng, Guang Xu, +7

International Immunopharmacology

Autoimmune DiseasePrevents Autoimmunity DiseasesImmunologyAutoimmunityInnate Immunity +3

Syntheses of cardanol-based cationic surfactants and their use in emulsion polymerisation

Rui Wang, Yuna Luo, Chuanjie Cheng, +4

Chemical Papers

EngineeringEmulsion PolymerisationPolymer ScienceAmphiphilic SystemChemistry +5

An Efficient Method for the Production of Cyclohexylamine from Cyclohexanone and Ammonia over Cu-Cr-La/γ-Al₂O₃

Shuanglin Qin, Pan Wang, Shuangping Huang, +5

Journal of the Korean Chemical Society

Chemical EngineeringMolecular SievesEngineeringEfficient MethodElectrosynthesis +7