Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

Alison Halliday, Richard Bulbulia, Leo H. Bonati, +896

The Lancet

Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

Bola S. Hanna, Laura Llaó Cid, Murat Iskar, +21

Immunity

InflammationImmune EvasionCancer ImmunosurveillanceImmunologyTumor Immunity +8

Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells

Nikolaos Ioannou, Angus Dalgleish, Alan M. Seddon, +4

British Journal of Cancer

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

Nikolaos Ioannou, Patrick R. Hagner, Matt Stokes, +18

Blood

Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, +2

BMC Cancer

Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, +3

International Journal of Oncology

Increased SensitivityOncologyPancreatic CancerMedicinePharmacology +12

T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities

Anna Vardi, Elisavet Vlachonikola, Despoina Papazoglou, +16

Clinical Cancer Research

A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

Piers Patten, Gerardo Ferrer, Shih-Shih Chen, +7

Frontiers in Immunology

Choices of Stent and Cerebral Protection in the Ongoing ACST-2 Trial: A Descriptive Study

D.D. de Waard, Alison Halliday, Gert J. de Borst, +420

European Journal of Vascular and Endovascular Surgery

Descriptive StudyInterventional NeuroradiologyEndovascular TechniqueCardiovascular DiseaseMedicine +11

Ibrutinib-based therapy reinvigorates CD8+ T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial

Despoina Papazoglou, Victoria Wang, Tait D. Shanafelt, +9

Blood

ImmunologyPathologyImmunotherapyTumor BiologyInflammation +19