Piyasena Hewawasam

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels

Valentin K. Gribkoff, John E. Starrett, Steven I. Dworetzky et al. · Nature Medicine · 2001 · 311 citations

Life Sciences, Neurology, Neuroscience +16

Synthesis and Structure−Activity Relationships of 3-Aryloxindoles:  A New Class of Calcium-Dependent, Large Conductance Potassium (Maxi-K) Channel Openers with Neuroprotective Properties

Piyasena Hewawasam, Matthew Erway, Sandra L. Moon et al. · Journal of Medicinal Chemistry · 2002 · 186 citations

Medicine, Medicinal Chemistry, Pharmacology +17

The synthesis and characterization of BMS-204352 (MaxiPost™) and related 3-fluorooxindoles as openers of maxi-K potassium channels

Piyasena Hewawasam, Valentin K. Gribkoff, Yadagiri Pendri et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 184 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

The synthesis and structure–activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-Dependent, large conductance, potassium (maxi-K) channel openers targeted for post-stroke neuroprotection

Piyasena Hewawasam, Wenhong Fan, Jay O. Knipe et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 102 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase

Robert G. Gentles, Min Ding, John A. Bender et al. · Journal of Medicinal Chemistry · 2014 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17