Lora K. Picton

The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species

Evan A. Bordt, Pascaline Clerc, Brian A. Roelofs et al. · Developmental Cell · 2017 · 564 citations · Full text

Reductive Stress, Reversible Mitochondrial Complex, Biochemistry +7

Design of protein-binding proteins from the target structure alone

Longxing Cao, Brian Coventry, Inna Goreshnik et al. · Nature · 2022 · 518 citations · Full text

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

Jonathan T. Sockolosky, Eleonora Trotta, Giulia Parisi et al. · Science · 2018 · 353 citations · Full text

Alternative evolutionary histories in the sequence space of an ancient protein

Tyler N. Starr, Lora K. Picton, Joseph W. Thornton · Nature · 2017 · 226 citations · Full text

Phylogenetics, Ancient Protein, Sequence Space +10

An engineered IL-2 partial agonist promotes CD8+ T cell stemness

Fei Mo, Zhiya Yu, Peng Li et al. · Nature · 2021 · 170 citations · Full text

Cell Therapy, Adaptive Immune System, Medicine +9