Yongpan An

Prediction of drug efficacy from transcriptional profiles with deep learning

Jie Zhu, Jingxiang Wang, Xin Wang et al. · Nature Biotechnology · 2021 · 178 citations

Drug Target, Engineering, Machine Learning +9

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression

Yao Dang, Yongpan An, Jinzhao He et al. · Aging Cell · 2019 · 101 citations · Full text

Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines

Boyue Huang, Dandan Zhong, Jie Zhu et al. · Aging Cell · 2020 · 50 citations · Full text

Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice

Abudumijiti Abulizi, Jianhua Ran, Yuwei Ye et al. · Food & Function · 2021 · 29 citations

Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress

Panshuang Qiao, Yi Sun, Yiming Wang et al. · Antioxidants · 2023 · 26 citations · Full text