Concepedia

Alan Costello

AC

8

Publications

180

Citations

8

H-Index

2017

Active since

Affiliations

Dublin City University(Current)

National Institute for Bioprocessing Research and Training

University College Dublin

Scripps Research Institute

Alan Costello is an author at Dublin City University specializing in medicine, cell biology, and gene expression.

Top concepts

MedicineCell BiologyGene ExpressionNon-coding RnaSystems BiologyCell EngineeringNatural SciencesOmicsBiologyGenetics

Publications per year

2017–2024

8

Publications

8

Continuous translation of circularized mRNA improves recombinant protein titer

Alan Costello, Nga T. Lao, Niall Barron et al. · Metabolic Engineering · 2019 · 39 citations

Continuous Translation, Natural Sciences, Molecular Biology +5

Leaky Expression of the TET-On System Hinders Control of Endogenous miRNA Abundance

Alan Costello, Nga T. Lao, Clair Gallagher et al. · Biotechnology Journal · 2018 · 35 citations

Biology, Single Gene Expression, Mirna Engineering +14

Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells

Paul Kelly, Colin Clarke, Alan Costello et al. · Metabolic Engineering · 2017 · 27 citations · Full text

Mitochondrial Function, Next-generation Sequencing, Genetics +7

Directed evolution of rRNA improves translation kinetics and recombinant protein yield

Fan Liu, Siniša Bratulić, Alan Costello et al. · Nature Communications · 2021 · 24 citations · Full text

Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14

Alan Costello, Orla Coleman, Nga T. Lao et al. · Journal of Biotechnology · 2018 · 20 citations

Systems Biology, Cell Regulation, Endogenous Mirna-378-3p Increases +9

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